One more for solution for those (like me) that have TREND MICRO OFFICE SCAN installed on your server.
Thanks to Marc Ozin over at webservertalk.com. This fixed my OWA loading problem immediately. Don't forget to clear your browser cache before testing.
<Taken from forum discussion>
I had a loooong trawl around and finally found a fix that works.
You don't by any chance have Trend Office Scan installed on your
exchange server?
If so, Office Scan might have configured MIME types on the Default Web
site and the Exchange virtudal directories.
It will add the value of .* application/octect-stream
The default is to have no entries in the MIME Types setting.
What you need to do is remove the MIME Types value that has been added
on the Default Web site as well as the Exchange, ExchAdmin, Public,
Exchange-oma, and ExchWeb virtual directories.
In IIS, right click on the properties of the website/virtudal
directory.
Go to the HTTP Headers tab.
Click the MIME Types button
Highlight and then remove the " .* application/octect-stream" entry.
Stop and start the default web site.
Don't forget when testing to see if it works you'll need to clear any
web cache/temporaty internet files to make sure your browser pulls the
files from the server.
Anyhow This solved my problem so I hope it works for you.
All the best
Marc
<end of excerpt>
Good luck to everyone. This one frustrated the $&%*# out of me for days!