We have to change our IP address for our NT server but we have about 100 domains in IIS all using the current IP.

Is there a quick way of changing every reference to the current IP to the new IP including under Advanced Multiple Web Site Configuration or is it a case of going thru each domain and changing it manually?

Have you thought about usin WINS or DNS?

Actually, it sounds like he wants to change the binding of each site from the current IP (normally listed as <all unassigned IPs> and they probably disabled socket pooling too, this is normally done when many NICs/IPs are bound on the same system) to the new IP that they are going to. Someone that you might want to try out would be Brett Hill at http://www.iisanswers.com/. He might be able to help you with that problem.