I will try. What distro and version are you using..RedHat, Debian, SuSE?
Did you install wine from source, or is it pre-installed in the distro? This does make a difference.
As Dapper Dan said, Codeweavers is probably the easiest, but it is not free.
Depending how Wine was installed depends how well it works.
What apps are you trying to run. It takes some special configuration to get some to run properly.
See this link for examples;
http://frankscorner.org/