Well, a corrupt driver is possible. When in safe mode, you are using the most basic element of your machine. So if you had a newer driver that has been corrupted, the one used in Safe Mode might work.
Try disabling all of your security applications, since it looks like you have a few of them. If the problem goes away, begin enabling them one by one. There might be something that is interfering.
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I swear, troubleshooting is a science: the best discoveries are always on accident...